InnateDB Protein
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IDBP-538016.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hmgb1
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Protein Name
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high mobility group box 1
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Synonyms
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amphoterin; DEF; HMG-1; Hmg1; p30; SBP-1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000114515
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InnateDB Gene
|
IDBG-209311 (Hmgb1)
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Protein Structure
|
|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.
Experimentally validated |
Total |
44
[view]
|
Protein-Protein |
41
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
1
[view]
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
62 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0070491
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repressing transcription factor binding
|
|
Biological Process |
GO:0002437
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inflammatory response to antigenic stimulus
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GO:0006288
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base-excision repair, DNA ligation
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GO:0017055
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negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
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GO:0033151
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V(D)J recombination
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GO:0043065
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positive regulation of apoptotic process
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GO:0043280
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positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
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GO:0043388
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positive regulation of DNA binding
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GO:0045087
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innate immune response (InnateDB)
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
|
|
Cellular Component |
|
PDB ID |
MGI:96113
|
InterPro |
IPR009071
High mobility group box domain
|
PFAM |
PF00505
PF09011
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PRINTS |
|
PIRSF |
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SMART |
SM00398
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
D3YVC6
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UniProt Splice Variant |
|
Entrez Gene |
619937
|
UniGene |
Mm.470617
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RefSeq |
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MGI ID |
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MGI Symbol |
Hmgb1
|
OMIM |
|
CCDS |
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HPRD |
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IMGT |
|
EMBL |
AC158782
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GenPept |
|
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