Version 5.4
Mus musculus Protein: Lgals3
Summary
InnateDB Protein IDBP-539112.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lgals3
Protein Name lectin, galactose binding, soluble 3
Synonyms gal3; GBP; L-34; Mac-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000119275
InnateDB Gene IDBG-154384 (Lgals3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0001501 skeletal system development
GO:0030198 extracellular matrix organization
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0009897 external side of plasma membrane
Protein Structure and Domains
PDB ID MGI:96778
InterPro IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00337
PRINTS
PIRSF
SMART SM00276
SM00908
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8C253
UniProt Splice Variant
Entrez Gene 16854
UniGene Mm.486633
RefSeq
MGI ID
MGI Symbol Lgals3
OMIM
CCDS CCDS26986
HPRD
IMGT
EMBL AC123665 AK089249 AK149783 AK155484 AK159536 AK170803 BC132328 BC138790 BC145419 CH466605
GenPept AAI32329 AAI38791 AAI45420 BAC40813 BAE29081 BAE33287 BAE35163 BAE42038 EDL20742 EDL20745

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca