InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hadhb

Summary

InnateDB Protein

IDBP-539361.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hadhb

Protein Name

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118296

InnateDB Gene

IDBG-145305 (Hadhb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003988	acetyl-CoA C-acyltransferase activity
GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex

Protein Structure and Domains

PDB ID

MGI:2136381

InterPro

IPR016039 Thiolase-like
IPR020616 Thiolase, N-terminal

PFAM

PF00108

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YXU1

UniProt Splice Variant

Entrez Gene

231086

UniGene

Mm.405989

RefSeq

MGI ID

MGI Symbol

Hadhb

OMIM

CCDS

HPRD

IMGT

EMBL

AC158757

GenPept