InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sqstm1

Summary

InnateDB Protein

IDBP-539505.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sqstm1

Protein Name

sequestosome 1

Synonyms

A170; OSF-6; Osi; p62; STAP; STONE14;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120442

InnateDB Gene

IDBG-168358 (Sqstm1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 98 experimentally validated interaction(s) in this database.
They are also associated with 172 interaction(s) predicted by orthology.

Experimentally validated
Total	98 [view]
Protein-Protein	98 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	172 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003712	transcription cofactor activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0045087	innate immune response (InnateDB)
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0000407	pre-autophagosomal structure
GO:0016235	aggresome

Protein Structure and Domains

PDB ID

MGI:107931

InterPro

IPR009060 UBA-like
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote

PFAM

PRINTS

PIRSF

SMART

SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6VD69

UniProt Splice Variant

Entrez Gene

18412

UniGene

Mm.473573

RefSeq

MGI ID

MGI Symbol

Sqstm1

OMIM

CCDS

HPRD

IMGT

EMBL

AL627187

GenPept