InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Smc2

Summary

InnateDB Protein

IDBP-539750.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Smc2

Protein Name

structural maintenance of chromosomes 2

Synonyms

5730502P04Rik; AI255214; AW545314; CAP-E; CAPE; Fin16; SMC-2; Smc2l1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114228

InnateDB Gene

IDBG-147370 (Smc2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	33 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0046982	protein heterodimerization activity

Biological Process

GO:0007076	mitotic chromosome condensation
GO:0010032	meiotic chromosome condensation
GO:0045132	meiotic chromosome segregation
GO:0051383	kinetochore organization

Cellular Component

GO:0000228	nuclear chromosome
GO:0000793	condensed chromosome
GO:0000796	condensin complex
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:106067

InterPro

IPR003395 RecF/RecN/SMC, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02463

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B1AWH6

UniProt Splice Variant

Entrez Gene

14211

UniGene

Mm.461800

RefSeq

MGI ID

MGI Symbol

Smc2

OMIM

CCDS

HPRD

IMGT

EMBL

AL732619

GenPept