InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fscn1

Summary

InnateDB Protein

IDBP-540715.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fscn1

Protein Name

fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)

Synonyms

AI663989; Fan1; fascin-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123347

InnateDB Gene

IDBG-207523 (Fscn1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	41 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008144	drug binding
GO:0030674	protein binding, bridging
GO:0051015	actin filament binding

Biological Process

GO:0016477	cell migration
GO:0051017	actin filament bundle assembly

Cellular Component

GO:0001725	stress fiber
GO:0030175	filopodium
GO:0071437	invadopodium

Protein Structure and Domains

PDB ID

MGI:1352745

InterPro

IPR008999 Actin cross-linking
IPR022768 Fascin domain

PFAM

PF06268

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YZR7

UniProt Splice Variant

Entrez Gene

14086

UniGene

Mm.289707

RefSeq

MGI ID

MGI Symbol

Fscn1

OMIM

CCDS

HPRD

IMGT

EMBL

AC144818

GenPept