InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sept2

Summary

InnateDB Protein

IDBP-541015.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sept2

Protein Name

septin 2

Synonyms

AW208991; mKIAA0158; Nedd-5; Nedd5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117517

InnateDB Gene

IDBG-183376 (Sept2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	64 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0030234	enzyme regulator activity
GO:0032947	protein complex scaffold
GO:0042802	identical protein binding

Biological Process

GO:0002036	regulation of L-glutamate transport
GO:0007049	cell cycle
GO:0031175	neuron projection development
GO:0032880	regulation of protein localization
GO:0050790	regulation of catalytic activity
GO:0051258	protein polymerization

Cellular Component

GO:0000145	exocyst
GO:0005730	nucleolus
GO:0005876	spindle microtubule
GO:0005886	plasma membrane
GO:0005938	cell cortex
GO:0009986	cell surface
GO:0015629	actin cytoskeleton
GO:0015630	microtubule cytoskeleton
GO:0030496	midbody
GO:0031105	septin complex
GO:0035869	ciliary transition zone
GO:0042995	cell projection
GO:0045202	synapse
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:97298

InterPro

IPR000038 Cell division protein GTP binding
IPR006703 AIG1
IPR008113 Septin 2
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00735
PF04548

PRINTS

PR01740

PIRSF

PIRSF006698

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6WYM0

UniProt Splice Variant

Entrez Gene

18000

UniGene

Mm.488666

RefSeq

MGI ID

MGI Symbol

Sept2

OMIM

CCDS

HPRD

IMGT

EMBL

AC108412

GenPept