Version 5.4
Mus musculus Gene: Sept2
Summary
InnateDB Gene IDBG-183376.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sept2
Gene Name septin 2
Synonyms AW208991; mKIAA0158; Nedd-5; Nedd5
Species Mus musculus
Ensembl Gene ENSMUSG00000026276
Encoded Proteins
IDBP-183378
septin 2
IDBP-254979
septin 2
IDBP-540053
septin 2
IDBP-538443
septin 2
IDBP-542439
septin 2
IDBP-542436
septin 2
IDBP-541317
septin 2
IDBP-531569
septin 2
IDBP-541015
septin 2
IDBP-622346
septin 2
IDBP-622347
septin 2
IDBP-622348
septin 2
IDBP-716679
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168385:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:93478964-93510260
Strand Forward strand
Band D
Transcripts
ENSMUST00000027495 ENSMUSP00000027495
ENSMUST00000112912 ENSMUSP00000108534
ENSMUST00000136182 ENSMUSP00000118621
ENSMUST00000131175 ENSMUSP00000120694
ENSMUST00000152778
ENSMUST00000153826 ENSMUSP00000114614
ENSMUST00000129211 ENSMUSP00000120511
ENSMUST00000149532 ENSMUSP00000115536
ENSMUST00000142401 ENSMUSP00000121974
ENSMUST00000150931 ENSMUSP00000117517
ENSMUST00000152476
ENSMUST00000157021 ENSMUSP00000134173
ENSMUST00000168776 ENSMUSP00000132850
ENSMUST00000172165 ENSMUSP00000127276
ENSMUST00000179353 ENSMUSP00000136366
ENSMUST00000188923
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 64 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0030234 enzyme regulator activity
GO:0032947 protein complex scaffold
GO:0042802 identical protein binding
Biological Process
GO:0000910 cytokinesis
GO:0002036 regulation of L-glutamate transport
GO:0006184 GTP catabolic process
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0007224 smoothened signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0031175 neuron projection development
GO:0032880 regulation of protein localization
GO:0042384 cilium assembly
GO:0050790 regulation of catalytic activity
GO:0051258 protein polymerization
Cellular Component
GO:0000145 exocyst
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005826 actomyosin contractile ring
GO:0005876 spindle microtubule
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0035869 ciliary transition zone
GO:0042995 cell projection
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0060170 ciliary membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168385
View Gene Order
ENSBTAG00000002608
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
cdc42_pathway
CDC42 signaling events
Cross-References
SwissProt
TrEMBL D3YV76 D3YYB1 D3YZU7 D3Z3C0 F6UKN5 F6WYM0
UniProt Splice Variant
Entrez Gene 18000
UniGene Mm.456228 Mm.488666
RefSeq NM_001159717 NM_001159718 NM_001159719 NM_010891 XM_006529239 XM_006529240 XM_006529241 XM_006529242
OMIM
CCDS CCDS15190
HPRD
IMGT
MGI ID MGI:97298
MGI Symbol Sept2
EMBL AC108412
GenPept
RNA Seq Atlas 18000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca