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InnateDB Protein
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IDBP-541590.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ints2
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Protein Name
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integrator complex subunit 2
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Synonyms
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2810417D08Rik; AA408260; AI987735; mKIAA1287;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000119084
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InnateDB Gene
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IDBG-206795 (Ints2)
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Protein Structure
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| Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (By similarity). {ECO:0000250}.
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| Subcellular Localization |
Nucleus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
16 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:1917672
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q80UK8
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| TrEMBL |
X1WI16
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| UniProt Splice Variant |
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| Entrez Gene |
70422
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| UniGene |
Mm.440906
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
Ints2
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL592065
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| GenPept |
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Version 5.4