Version 5.4
Mus musculus Gene: Ints2
Summary
InnateDB Gene IDBG-206795.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ints2
Gene Name integrator complex subunit 2
Synonyms 2810417D08Rik; AA408260; AI987735; mKIAA1287
Species Mus musculus
Ensembl Gene ENSMUSG00000018068
Encoded Proteins
IDBP-206797
integrator complex subunit 2
IDBP-265379
integrator complex subunit 2
IDBP-718183
IDBP-541590
integrator complex subunit 2
IDBP-538939
integrator complex subunit 2
IDBP-540570
integrator complex subunit 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108506:
INTS2 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:86210681-86257575
Strand Reverse strand
Band C
Transcripts
ENSMUST00000018212 ENSMUSP00000018212
ENSMUST00000108039 ENSMUSP00000103674
ENSMUST00000134828 ENSMUSP00000135300
ENSMUST00000146421
ENSMUST00000134883
ENSMUST00000127745
ENSMUST00000139285 ENSMUSP00000119084
ENSMUST00000132024 ENSMUSP00000114859
ENSMUST00000136469 ENSMUSP00000116633
ENSMUST00000130614
ENSMUST00000141756
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0032039 integrator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108506
View Gene Order
ENSBTAG00000012070
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.396833 Mm.440906
RefSeq NM_027421 XM_006534176 XM_006534177 XM_006534178 XM_006534179 XM_006534180 XM_006534181 XM_006534182
OMIM
CCDS CCDS25198
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca