InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fgf3

Summary

InnateDB Protein

IDBP-541766.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fgf3

Protein Name

fibroblast growth factor 3

Synonyms

Fgf-3; Int-2; Int-P;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115205

InnateDB Gene

IDBG-212945 (Fgf3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005104	fibroblast growth factor receptor binding
GO:0008083	growth factor activity

Biological Process

GO:0001759	organ induction
GO:0008284	positive regulation of cell proliferation
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0030916	otic vesicle formation
GO:0036342	post-anal tail morphogenesis
GO:0048538	thymus development
GO:0048752	semicircular canal morphogenesis
GO:0055026	negative regulation of cardiac muscle tissue development

Cellular Component

GO:0005576	extracellular region
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

MGI:95517

InterPro

IPR002209 Fibroblast growth factor family
IPR008996 Cytokine, IL-1-like
IPR028142 IL-1 family/FGF family

PFAM

PRINTS

PR00263
PR00262

PIRSF

SMART

SM00442

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YWD4

UniProt Splice Variant

Entrez Gene

14174

UniGene

Mm.4947

RefSeq

MGI ID

MGI Symbol

Fgf3

OMIM

CCDS

HPRD

IMGT

EMBL

AC149593

GenPept