Version 5.4
Mus musculus Protein: Ldhb
Summary
InnateDB Protein IDBP-541976.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ldhb
Protein Name lactate dehydrogenase B
Synonyms AI790582; H-Ldh; Ldh-2; LDH-B; LDH-H; Ldh2;
Species Mus musculus
Ensembl Protein ENSMUSP00000116014
InnateDB Gene IDBG-196960 (Ldhb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004459 L-lactate dehydrogenase activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019900 kinase binding
GO:0042802 identical protein binding
GO:0051287 NAD binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006089 lactate metabolic process
GO:0006096 glycolytic process
GO:0019674 NAD metabolic process
GO:0044262 cellular carbohydrate metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:96763
InterPro IPR001088 Glycoside hydrolase, family 4
IPR001236 Lactate/malate dehydrogenase, N-terminal
IPR001557 L-lactate/malate dehydrogenase
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR022383 Lactate/malate dehydrogenase, C-terminal
PFAM PF02056
PF00056
PF02866
PRINTS PR00732
PR00086
PIRSF PIRSF000102
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z7F0
UniProt Splice Variant
Entrez Gene 16832
UniGene Mm.9745
RefSeq
MGI ID
MGI Symbol Ldhb
OMIM
CCDS
HPRD
IMGT
EMBL AC142413
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca