Version 5.4
Mus musculus Protein: Igf2
Summary
InnateDB Protein IDBP-542006.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Igf2
Protein Name insulin-like growth factor 2
Synonyms AL033362; Igf-2; Igf-II; M6pr; Mpr; Peg2;
Species Mus musculus
Ensembl Protein ENSMUSP00000122653
InnateDB Gene IDBG-212623 (Igf2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005179 hormone activity
GO:0005515 protein binding
GO:0008083 growth factor activity
Biological Process
GO:0007565 female pregnancy
GO:0007613 memory
GO:0009314 response to radiation
GO:0009887 organ morphogenesis
GO:0031017 exocrine pancreas development
GO:0031667 response to nutrient levels
GO:0032355 response to estradiol
GO:0035094 response to nicotine
GO:0042060 wound healing
GO:0042104 positive regulation of activated T cell proliferation
GO:0042493 response to drug
GO:0043410 positive regulation of MAPK cascade
GO:0045471 response to ethanol
GO:0045840 positive regulation of mitosis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0051146 striated muscle cell differentiation
GO:0051897 positive regulation of protein kinase B signaling
GO:0071260 cellular response to mechanical stimulus
GO:0090031 positive regulation of steroid hormone biosynthetic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:96434
InterPro IPR016179 Insulin-like
IPR022334 Insulin-like growth factor II
IPR022350 Insulin-like growth factor
IPR022352 Insulin family
PFAM PF00049
PRINTS PR02006
PR02002
PR00276
PIRSF
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z4N4
UniProt Splice Variant
Entrez Gene 16002
UniGene Mm.419447
RefSeq
MGI ID
MGI Symbol Igf2
OMIM
CCDS
HPRD
IMGT
EMBL AC013548
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca