Version 5.4
Mus musculus Protein: Ing2
Summary
InnateDB Protein IDBP-542148.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ing2
Protein Name inhibitor of growth family, member 2
Synonyms 2810011M06Rik; Ing1l; Ing2b; P33ING2;
Species Mus musculus
Ensembl Protein ENSMUSP00000124792
InnateDB Gene IDBG-154718 (Ing2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0032403 protein complex binding
GO:0035064 methylated histone binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0016568 chromatin modification
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0043065 positive regulation of apoptotic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0016580 Sin3 complex
GO:0016602 CCAAT-binding factor complex
Protein Structure and Domains
PDB ID MGI:1916510
InterPro IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00628
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E0CXA7
UniProt Splice Variant
Entrez Gene 69260
UniGene Mm.430733
RefSeq
MGI ID
MGI Symbol Ing2
OMIM
CCDS
HPRD
IMGT
EMBL AC107236
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca