InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mycn

Summary

InnateDB Protein

IDBP-542340.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mycn

Protein Name

v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Synonyms

bHLHe37; c-nmyc; N-myc; Nmyc; Nmyc-1; Nmyc1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114225

InnateDB Gene

IDBG-128962 (Mycn)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	8 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001502	cartilage condensation
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0006355	regulation of transcription, DNA-templated
GO:0008284	positive regulation of cell proliferation
GO:0010942	positive regulation of cell death
GO:0030324	lung development
GO:0042733	embryonic digit morphogenesis
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048704	embryonic skeletal system morphogenesis
GO:0048712	negative regulation of astrocyte differentiation
GO:0048754	branching morphogenesis of an epithelial tube
GO:2000378	negative regulation of reactive oxygen species metabolic process