InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACTR2

Summary

InnateDB Protein

IDBP-54241.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACTR2

Protein Name

ARP2 actin-related protein 2 homolog (yeast)

Synonyms

ARP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000367220

InnateDB Gene

IDBG-54239 (ACTR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 79 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	79 [view]
Protein-Protein	79 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005524	ATP binding

Biological Process

GO:0006928	cellular component movement
GO:0007163	establishment or maintenance of cell polarity
GO:0008356	asymmetric cell division
GO:0016344	meiotic chromosome movement towards spindle pole
GO:0016482	cytoplasmic transport
GO:0030036	actin cytoskeleton organization
GO:0033206	cytokinesis after meiosis
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087	innate immune response
GO:0051321	meiotic cell cycle
GO:0051653	spindle localization

Cellular Component

GO:0005829	cytosol
GO:0005885	Arp2/3 protein complex
GO:0005938	cell cortex
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0030478	actin cap
GO:0042995	cell projection
GO:0070062	extracellular vesicular exosome