InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Grb10

Summary

InnateDB Protein

IDBP-542785.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Grb10

Protein Name

growth factor receptor bound protein 10

Synonyms

5730571D09Rik; AI325020; Meg1; mKIAA0207;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118350

InnateDB Gene

IDBG-150690 (Grb10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	21 [view]
Protein-Protein	21 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005070	SH3/SH2 adaptor activity
GO:0005158	insulin receptor binding
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0008286	insulin receptor signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0042327	positive regulation of phosphorylation
GO:0045719	negative regulation of glycogen biosynthetic process
GO:0048009	insulin-like growth factor receptor signaling pathway

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

MGI:103232

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q80Z28

UniProt Splice Variant

Entrez Gene

14783

UniGene

Mm.469950

RefSeq

MGI ID

MGI Symbol

Grb10

OMIM

CCDS

HPRD

IMGT

EMBL

AB106541 AL645803 AL663087

GenPept

BAC66117