InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pms2

Summary

InnateDB Protein

IDBP-542806.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pms2

Protein Name

postmeiotic segregation increased 2 (S. cerevisiae)

Synonyms

AW555130; Pmsl2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119875

InnateDB Gene

IDBG-259679 (Pms2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0030983	mismatched DNA binding
GO:0032138	single base insertion or deletion binding
GO:0032407	MutSalpha complex binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006298	mismatch repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007126	meiotic nuclear division
GO:0016446	somatic hypermutation of immunoglobulin genes
GO:0016447	somatic recombination of immunoglobulin gene segments
GO:0042493	response to drug

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton
GO:0032389	MutLalpha complex

Protein Structure and Domains

PDB ID

MGI:104288

InterPro

IPR002099 DNA mismatch repair protein family
IPR003594 Histidine kinase-like ATPase, ATP-binding domain
IPR013507 DNA mismatch repair protein, C-terminal
IPR014790 MutL, C-terminal, dimerisation
IPR020568 Ribosomal protein S5 domain 2-type fold

PFAM

PF02518
PF13581
PF01119
PF08676

PRINTS

PIRSF

SMART

SM00387
SM00853

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite