Version 5.4
Mus musculus Protein: F8
Summary
InnateDB Protein IDBP-542818.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol F8
Protein Name coagulation factor VIII
Synonyms Cf-8; Cf8; FVIII;
Species Mus musculus
Ensembl Protein ENSMUSP00000114207
InnateDB Gene IDBG-157124 (F8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0005507 copper ion binding
Biological Process
GO:0006508 proteolysis
GO:0007597 blood coagulation, intrinsic pathway
GO:0030168 platelet activation
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:88383
InterPro IPR008972 Cupredoxin
IPR011707 Multicopper oxidase, type 3
PFAM PF07732
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YW61
UniProt Splice Variant
Entrez Gene 14069
UniGene Mm.1805
RefSeq
MGI ID
MGI Symbol F8
OMIM
CCDS
HPRD
IMGT
EMBL AL731844 AL808110
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca