Version 5.4
Mus musculus Protein: Crem
Summary
InnateDB Protein IDBP-542982.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crem
Protein Name cAMP responsive element modulator
Synonyms ICER; ICERI;
Species Mus musculus
Ensembl Protein ENSMUSP00000118578
InnateDB Gene IDBG-127729 (Crem)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006687 glycosphingolipid metabolic process
GO:0007283 spermatogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:88495
InterPro IPR001630 cAMP response element binding (CREB) protein
IPR004827 Basic-leucine zipper domain
PFAM PF00170
PF07716
PRINTS PR00041
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q78Z98
UniProt Splice Variant
Entrez Gene 12916
UniGene Mm.5244
RefSeq NP_001104325
MGI ID
MGI Symbol Crem
OMIM
CCDS CCDS50209
HPRD
IMGT
EMBL AC117589 AJ292222
GenPept CAC27134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca