InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Abl1

Summary

InnateDB Protein

IDBP-543037.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Abl1

Protein Name

c-abl oncogene 1, non-receptor tyrosine kinase

Synonyms

Abl; AI325092; c-Abl; E430008G22Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117748

InnateDB Gene

IDBG-158216 (Abl1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 268 interaction(s) predicted by orthology.

Experimentally validated
Total	60 [view]
Protein-Protein	60 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	268 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0019904	protein domain specific binding

Biological Process

GO:0018108	peptidyl-tyrosine phosphorylation
GO:0045087	innate immune response (InnateDB)
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0051726	regulation of cell cycle

Cellular Component

GO:0005829	cytosol
GO:0031252	cell leading edge

Protein Structure and Domains

PDB ID

MGI:87859

InterPro

IPR001452 SH3 domain
IPR003646 SH3-like domain, bacterial-type
IPR011511 Variant SH3 domain

PFAM

PF00018
PF14604
PF08239
PF08460
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00326
SM00287

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AV23

UniProt Splice Variant

Entrez Gene

11350

UniGene

Mm.1318

RefSeq

MGI ID

MGI Symbol

Abl1

OMIM

CCDS

HPRD

IMGT

EMBL

AL929275

GenPept