Version 5.4
Homo sapiens Protein: PTTG1IP
Summary
InnateDB Protein IDBP-5576.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTTG1IP
Protein Name pituitary tumor-transforming 1 interacting protein
Synonyms C21orf1; C21orf3; PBF;
Species Homo sapiens
Ensembl Protein ENSP00000328325
InnateDB Gene IDBG-5574 (PTTG1IP)
Protein Structure
UniProt Annotation
Function May facilitate PTTG1 nuclear translocation.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:10781616}. Nucleus {ECO:0000269PubMed:10781616}. Note=According to PubMed:10781616, it is found in the cytoplasm and the nucleus.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004872 receptor activity
Biological Process
GO:0006606 protein import into nucleus
GO:0007275 multicellular organismal development
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR016201 Plexin-like fold
PFAM
PRINTS
PIRSF
SMART SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53801
PhosphoSite PhosphoSite-P53801
TrEMBL A8K274
UniProt Splice Variant
Entrez Gene 754
UniGene Hs.708709
RefSeq NP_004330
HUGO HGNC:13524
OMIM 603784
CCDS CCDS13715
HPRD 04807
IMGT
EMBL AF149785 AK290139 AK315626 AL163300 BC000415 BC012858 BC019295 BC020983 BC031097 BC034250 CH471079 Z50022
GenPept AAF73770 AAH00415 AAH12858 AAH19295 AAH20983 AAH31097 AAH34250 BAF82828 BAG37994 CAA90325 CAB90552 EAX09386 EAX09388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca