InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FOXF2

Summary

InnateDB Protein

IDBP-56010.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FOXF2

Protein Name

forkhead box F2

Synonyms

FKHL6; FREAC-2; FREAC2;

Species

Homo sapiens

Ensembl Protein

ENSP00000259806

InnateDB Gene

IDBG-56008 (FOXF2)

Protein Structure

UniProt Annotation

Function

Probable transcription activator for a number of lung- specific genes.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Lung and placenta.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008134	transcription factor binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001837	epithelial to mesenchymal transition
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030198	extracellular matrix organization
GO:0042249	establishment of planar polarity of embryonic epithelium
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048566	embryonic digestive tract development
GO:0048596	embryonic camera-type eye morphogenesis
GO:0048806	genitalia development
GO:0060021	palate development