InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BCAM

Summary

InnateDB Protein

IDBP-56641.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BCAM

Protein Name

basal cell adhesion molecule (Lutheran blood group)

Synonyms

AU; CD239; LU; MSK19;

Species

Homo sapiens

Ensembl Protein

ENSP00000270233

InnateDB Gene

IDBG-56639 (BCAM)

Protein Structure

UniProt Annotation

Function

Laminin alpha-5 receptor. May mediate intracellular signaling. {ECO:0000269PubMed:9616226}.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005055	laminin receptor activity
GO:0005515	protein binding
GO:0043236	laminin binding

Biological Process

GO:0007155	cell adhesion
GO:0007160	cell-matrix adhesion
GO:0007165	signal transduction

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0070062	extracellular vesicular exosome