InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STC2

Summary

InnateDB Protein

IDBP-58124.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STC2

Protein Name

stanniocalcin 2

Synonyms

STC-2; STCRP;

Species

Homo sapiens

Ensembl Protein

ENSP00000265087

InnateDB Gene

IDBG-58122 (STC2)

Protein Structure

UniProt Annotation

Function

Has an anti-hypocalcemic action on calcium and phosphate homeostasis.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	12 [view]
Protein-DNA	9 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005179	hormone activity
GO:0005515	protein binding

Biological Process

GO:0006874	cellular calcium ion homeostasis
GO:0006979	response to oxidative stress
GO:0007166	cell surface receptor signaling pathway
GO:0007267	cell-cell signaling
GO:0007566	embryo implantation
GO:0007584	response to nutrient
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0033280	response to vitamin D
GO:0034976	response to endoplasmic reticulum stress
GO:0040015	negative regulation of multicellular organism growth
GO:0043434	response to peptide hormone
GO:0046697	decidualization
GO:0055074	calcium ion homeostasis
GO:0071456	cellular response to hypoxia
GO:2001256	regulation of store-operated calcium entry