InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZEB2

Summary

InnateDB Protein

IDBP-584141.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZEB2

Protein Name

zinc finger E-box binding homeobox 2

Synonyms

HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000443792

InnateDB Gene

IDBG-71713 (ZEB2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	29 [view]
Protein-Protein	26 [view]
Protein-DNA	1 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0019208	phosphatase regulator activity
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0007399	nervous system development
GO:0045636	positive regulation of melanocyte differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048023	positive regulation of melanin biosynthetic process
GO:0048066	developmental pigmentation
GO:0097324	melanocyte migration
GO:1903056	regulation of melanosome organization