InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TUBB3

Summary

InnateDB Protein

IDBP-584514.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TUBB3

Protein Name

Melanocyte-stimulating hormone receptor

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000451560

InnateDB Gene

IDBG-48628 (TUBB3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004930	G-protein coupled receptor activity
GO:0005200	structural constituent of cytoskeleton
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007017	microtubule-based process
GO:0007186	G-protein coupled receptor signaling pathway
GO:0051258	protein polymerization

Cellular Component

GO:0005874	microtubule
GO:0016021	integral component of membrane
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR000217 Tubulin
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000761 Melanocyte-stimulating hormone receptor
IPR001671 Melanocortin/ACTH receptor
IPR001908 Melanocortin receptor
IPR002452 Alpha tubulin
IPR002453 Beta tubulin
IPR002454 Gamma tubulin
IPR002967 Delta tubulin
IPR003008 Tubulin/FtsZ, GTPase domain
IPR004057 Epsilon tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR017452 GPCR, rhodopsin-like, 7TM
IPR018316 Tubulin/FtsZ, 2-layer sandwich domain

PFAM

PF00001
PF00091
PF03953

PRINTS