InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IRF6

Summary

InnateDB Protein

IDBP-585136.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IRF6

Protein Name

interferon regulatory factor 6

Synonyms

LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000440532

InnateDB Gene

IDBG-106452 (IRF6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	14 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000975	regulatory region DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007050	cell cycle arrest
GO:0008285	negative regulation of cell proliferation
GO:0019221	cytokine-mediated signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0060337	type I interferon signaling pathway
GO:0060644	mammary gland epithelial cell differentiation