Version 5.4
Homo sapiens Protein: CEP57
Summary
InnateDB Protein IDBP-585402.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP57
Protein Name centrosomal protein 57kDa
Synonyms MVA2; PIG8; TSP57;
Species Homo sapiens
Ensembl Protein ENSP00000443436
InnateDB Gene IDBG-68511 (CEP57)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 102 experimentally validated interaction(s) in this database.
Experimentally validated
Total 102 [view]
Protein-Protein 99 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043015 gamma-tubulin binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0007286 spermatid development
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0034453 microtubule anchoring
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR024957 Cep57 centrosome microtubule-binding domain
PFAM PF06657
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XR8
PhosphoSite PhosphoSite-Q86XR8
TrEMBL F5H1B0
UniProt Splice Variant
Entrez Gene 9702
UniGene Hs.708311
RefSeq NP_001230705
HUGO HGNC:30794
OMIM 607951
CCDS CCDS58167
HPRD 16261
IMGT
EMBL AK291245 AK293277 AP001877 AY225092 AY239292 BC001233 BC029385 BC039711 D42054
GenPept AAH01233 AAH29385 AAH39711 AAO73938 AAP72184 BAA07654 BAF83934 BAG56806

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca