InnateDB Protein
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IDBP-586114.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GRP
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Protein Name
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gastrin-releasing peptide
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Synonyms
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BN; GRP-10; preproGRP; proGRP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000434101
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InnateDB Gene
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IDBG-4030 (GRP)
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Protein Structure
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Function |
GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP- receptor gene expression, long-term potentiation, and amygdala- dependent memory for fear (By similarity). {ECO:0000250}.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
0
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Protein-DNA |
0
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Protein-RNA |
3
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000874
Bombesin/neuromedin-B/ranatensin peptide family
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PFAM |
PF02044
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P07492
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PhosphoSite |
PhosphoSite-P07492
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
2922
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UniGene |
Hs.153444
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RefSeq |
NP_001012531
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HUGO |
HGNC:4605
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OMIM |
137260
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CCDS |
CCDS45878
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HPRD |
08845
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IMGT |
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EMBL |
AC067859
BC004488
BT006803
CH471096
K02054
M12511
M12512
M12550
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GenPept |
AAA52611
AAA52612
AAA52613
AAH04488
AAP35449
EAW63091
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