InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRMT1

Summary

InnateDB Protein

IDBP-586613.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRMT1

Protein Name

protein arginine methyltransferase 1

Synonyms

ANM1; HCP1; HRMT1L2; IR1B4;

Species

Homo sapiens

Ensembl Protein

ENSP00000432349

InnateDB Gene

IDBG-63299 (PRMT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 206 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	206 [view]
Protein-Protein	201 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008168	methyltransferase activity
GO:0008276	protein methyltransferase activity
GO:0016740	transferase activity

Biological Process

GO:0006479	protein methylation
GO:0008152	metabolic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR003402 tRNA transferase Trm5/Tyw2
IPR007848 Methyltransferase small domain
IPR010456 Ribosomal L11 methyltransferase, PrmA
IPR013216 Methyltransferase type 11
IPR025799 Protein arginine N-methyltransferase
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF02475
PF05175
PF06325
PF08241
PF05185

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-