InnateDB Protein
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IDBP-586796.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BCL2L13
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Protein Name
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BCL2-like 13 (apoptosis facilitator)
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Synonyms
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BCL-RAMBO; Bcl2-L-13; MIL1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000434764
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InnateDB Gene
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IDBG-1018 (BCL2L13)
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Protein Structure
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Function |
May promote the activation of caspase-3 and apoptosis.
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Subcellular Localization |
Isoform 2: Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000305}.Isoform 1: Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
5
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008656
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cysteine-type endopeptidase activator activity involved in apoptotic process
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Biological Process |
GO:0006915
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apoptotic process
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GO:0006919
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activation of cysteine-type endopeptidase activity involved in apoptotic process
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GO:0042981
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regulation of apoptotic process
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Cellular Component |
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PDB ID |
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InterPro |
IPR002475
Bcl2-like
IPR026298
Blc2 family
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PFAM |
PF00452
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PRINTS |
PR01862
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BXK5
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PhosphoSite |
PhosphoSite-Q9BXK5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
23786
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UniGene |
Hs.743849
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RefSeq |
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HUGO |
HGNC:17164
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OMIM |
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CCDS |
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HPRD |
09822
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IMGT |
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EMBL |
AC006285
AF146568
AF183411
AF246665
AF325209
AK056248
AL133029
BC007658
BC016037
CR456521
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GenPept |
AAF03602
AAG09680
AAH07658
AAH16037
AAK15150
AAK27358
BAG51659
CAB61361
CAG30407
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