Homo sapiens Protein: CYP46A1
Summary
InnateDB Protein IDBP-587060.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP46A1
Protein Name cytochrome P450, family 46, subfamily A, polypeptide 1
Synonyms CP46; CYP46;
Species Homo sapiens
Ensembl Protein ENSP00000450553
InnateDB Gene IDBG-19788 (CYP46A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0033781 cholesterol 24-hydroxylase activity
Biological Process
GO:0006699 bile acid biosynthetic process
GO:0006707 cholesterol catabolic process
GO:0006805 xenobiotic metabolic process
GO:0007399 nervous system development
GO:0008206 bile acid metabolic process
GO:0016125 sterol metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
PFAM PF00067
PRINTS PR00385
PR00463
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y6A2
PhosphoSite PhosphoSite-Q9Y6A2
TrEMBL
UniProt Splice Variant
Entrez Gene 10858
UniGene Hs.25121
RefSeq
HUGO HGNC:2641
OMIM 604087
CCDS
HPRD 04970
IMGT
EMBL AF094480 AK090886 AK295216 AL136000 AL160313 BC022539
GenPept AAD41244 AAH22539 BAC03539 BAG58210