Version 5.4
Homo sapiens Protein: FANCM
Summary
InnateDB Protein IDBP-587187.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FANCM
Protein Name Fanconi anemia, complementation group M
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000452033
InnateDB Gene IDBG-5587 (FANCM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004518 nuclease activity
Biological Process
GO:0006259 DNA metabolic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006166 ERCC4 domain
IPR010994 RuvA domain 2-like
IPR011335 Restriction endonuclease type II-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF02732
PRINTS
PIRSF
SMART SM00891
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YJS3
UniProt Splice Variant
Entrez Gene 57697
UniGene Hs.509229
RefSeq
HUGO HGNC:23168
OMIM 609644
CCDS
HPRD 13876
IMGT
EMBL AL121809
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca