Version 5.4
Homo sapiens Protein: PCK2
Summary
InnateDB Protein IDBP-587900.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCK2
Protein Name phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Synonyms PEPCK; PEPCK-M; PEPCK2;
Species Homo sapiens
Ensembl Protein ENSP00000454011
InnateDB Gene IDBG-3497 (PCK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0017076 purine nucleotide binding
Biological Process
GO:0006094 gluconeogenesis
GO:0016310 phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising
IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal
PFAM PF00821
PRINTS
PIRSF PIRSF001348
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNG4
UniProt Splice Variant
Entrez Gene 5106
UniGene Hs.75812
RefSeq NP_001278485
HUGO HGNC:8725
OMIM 614095
CCDS
HPRD 02026
IMGT
EMBL AK301400 AK316206 AL136295
GenPept BAG62935 BAH14577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca