InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPLP0

Summary

InnateDB Protein

IDBP-588132.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPLP0

Protein Name

ribosomal protein, large, P0

Synonyms

L10E; LP0; P0; PRLP0; RPP0;

Species

Homo sapiens

Ensembl Protein

ENSP00000449328

InnateDB Gene

IDBG-60241 (RPLP0)

Protein Structure

UniProt Annotation

Function

Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

Subcellular Localization

Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0042254	ribosome biogenesis
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0036464	cytoplasmic ribonucleoprotein granule
GO:0070062	extracellular vesicular exosome