Version 5.4
Homo sapiens Protein: CHD4
Summary
InnateDB Protein IDBP-588522.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHD4
Protein Name chromodomain helicase DNA binding protein 4
Synonyms CHD-4; Mi-2b; Mi2-BETA;
Species Homo sapiens
Ensembl Protein ENSP00000437506
InnateDB Gene IDBG-14532 (CHD4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 115 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
Experimentally validated
Total 115 [view]
Protein-Protein 115 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 27 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Biological Process
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0008152 metabolic process
GO:0051225 spindle assembly
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
IPR012958 CHD, N-terminal
PFAM PF00505
PF09011
PF08073
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q05CG6
UniProt Splice Variant
Entrez Gene 1108
UniGene Hs.605320
RefSeq
HUGO HGNC:1919
OMIM 603277
CCDS
HPRD 04472
IMGT
EMBL AC006064 BC014964 BC025962
GenPept AAH14964 AAH25962

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca