InnateDB Protein
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IDBP-590409.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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INADL
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Protein Name
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InaD-like (Drosophila)
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Synonyms
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Cipp; hINADL; InaD-like; PATJ;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000433669
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InnateDB Gene
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IDBG-99328 (INADL)
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Protein Structure
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Function |
Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. {ECO:0000269PubMed:11927608}.
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Subcellular Localization |
Membrane. Cell junction, tight junction. Apical cell membrane. Cytoplasm, perinuclear region. Note=Localized in the paranodal region of myelinating Schwann cells (By similarity). Membrane-associated. Localizes to tight junctions in epithelial cells. Also found at the apical plasma membrane. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in bladder, testis, ovary, small intestine, colon, heart, skeletal muscle, pancreas and cerebellum in the brain. {ECO:0000269PubMed:11964389, ECO:0000269PubMed:9280290}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
49
[view]
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Protein-Protein |
47
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001478
PDZ domain
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PFAM |
PF00595
PF13180
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PRINTS |
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PIRSF |
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SMART |
SM00228
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NI35
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PhosphoSite |
PhosphoSite-Q8NI35
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10207
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UniGene |
Hs.478125
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RefSeq |
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HUGO |
HGNC:28881
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OMIM |
603199
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CCDS |
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HPRD |
04434
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IMGT |
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EMBL |
AB044807
AC097064
AF397170
AJ001306
AJ224747
AJ224748
AL136458
AL353802
AL449143
AL590374
BC021135
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GenPept |
AAH21135
AAM28433
BAB19683
CAA04666
CAA12112
CAA12113
CAH70416
CAH70418
CAH70420
CAI15923
CAI15925
CAI21733
CAI21734
CAI21737
CAI22258
CAI22260
CAI22262
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