InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KPNB1

Summary

InnateDB Protein

IDBP-591309.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KPNB1

Protein Name

karyopherin (importin) beta 1

Synonyms

IMB1; Impnb; IPO1; IPOB; NTF97;

Species

Homo sapiens

Ensembl Protein

ENSP00000438253

InnateDB Gene

IDBG-56053 (KPNB1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 182 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	182 [view]
Protein-Protein	179 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008139	nuclear localization sequence binding
GO:0008270	zinc ion binding
GO:0008536	Ran GTPase binding
GO:0019899	enzyme binding
GO:0019904	protein domain specific binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000060	protein import into nucleus, translocation
GO:0006309	apoptotic DNA fragmentation
GO:0006606	protein import into nucleus
GO:0006607	NLS-bearing protein import into nucleus
GO:0006610	ribosomal protein import into nucleus
GO:0006915	apoptotic process
GO:0006921	cellular component disassembly involved in execution phase of apoptosis
GO:0016032	viral process
GO:0019058	viral life cycle
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0075733	intracellular transport of virus

Cellular Component

GO:0005634	nucleus
GO:0005635	nuclear envelope
GO:0005643	nuclear pore
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0031965	nuclear membrane
GO:0070062	extracellular vesicular exosome
GO:0071782	endoplasmic reticulum tubular network