Version 5.4
Homo sapiens Protein: ADAR
Summary
InnateDB Protein IDBP-592266.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAR
Protein Name adenosine deaminase, RNA-specific
Synonyms ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136;
Species Homo sapiens
Ensembl Protein ENSP00000431794
InnateDB Gene IDBG-102968 (ADAR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 37 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0004000 adenosine deaminase activity
Biological Process
GO:0006396 RNA processing
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000607 Double-stranded RNA-specific adenosine deaminase (DRADA)
IPR002466 Adenosine deaminase/editase
IPR014720 Double-stranded RNA-binding domain
PFAM PF02295
PF02137
PF00035
PRINTS
PIRSF
SMART SM00550
SM00552
SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YCK3
UniProt Splice Variant
Entrez Gene 103
UniGene Hs.659290
RefSeq XP_006711173
HUGO HGNC:225
OMIM 146920
CCDS
HPRD 07528
IMGT
EMBL AL592078 AL606500 AL691488 CH471121
GenPept EAW53184 EAW53189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca