Version 5.4
Homo sapiens Protein: TSEN15
Summary
InnateDB Protein IDBP-593397.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSEN15
Protein Name tRNA splicing endonuclease 15 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436996
InnateDB Gene IDBG-105345 (TSEN15)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000213 tRNA-intron endonuclease activity
Biological Process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR018593 tRNA-splicing endonuclease subunit Sen15
PFAM PF09631
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PPN1
UniProt Splice Variant
Entrez Gene 116461
UniGene Hs.705867
RefSeq NP_001287695
HUGO HGNC:16791
OMIM 608756
CCDS CCDS72993
HPRD 12292
IMGT
EMBL AL157943 AL158011
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca