Version 5.4
Homo sapiens Protein: SIPA1
Summary
InnateDB Protein IDBP-593756.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIPA1
Protein Name signal-induced proliferation-associated 1
Synonyms SPA1;
Species Homo sapiens
Ensembl Protein ENSP00000433686
InnateDB Gene IDBG-242018 (SIPA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000331 Rap GTPase activating protein domain
IPR001478 PDZ domain
PFAM PF02145
PF00595
PF13180
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6RY50
UniProt Splice Variant
Entrez Gene 6494
UniGene Hs.530477
RefSeq
HUGO HGNC:10885
OMIM 602180
CCDS
HPRD 03713
IMGT
EMBL AP001362
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca