Homo sapiens Protein: FBXO21
Summary
InnateDB Protein IDBP-59436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO21
Protein Name F-box protein 21
Synonyms FBX21;
Species Homo sapiens
Ensembl Protein ENSP00000328187
InnateDB Gene IDBG-59432 (FBXO21)
Protein Structure
UniProt Annotation
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001810 F-box domain
IPR011722 Hemimethylated DNA-binding domain
PFAM PF00646
PF12937
PF13013
PF08755
PRINTS
PIRSF
SMART SM00256
SM00992
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94952
PhosphoSite PhosphoSite-O94952
TrEMBL A0A024RBR2
UniProt Splice Variant
Entrez Gene 23014
UniGene Hs.740376
RefSeq NP_296373
HUGO HGNC:13592
OMIM 609095
CCDS CCDS9184
HPRD 09948
IMGT
EMBL AB020682 AC026364 AC026368 AF174601 AK001699 AL136899 BC091496 CH471054
GenPept AAF04522 AAH91496 BAA74898 BAG50962 CAB66833 EAW98102 EAW98104 EAW98105