InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KRT8

Summary

InnateDB Protein

IDBP-594937.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KRT8

Protein Name

keratin 8

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000449404

InnateDB Gene

IDBG-35198 (KRT8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 79 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	79 [view]
Protein-Protein	79 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0097110	scaffold protein binding

Biological Process

GO:0016032	viral process
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0045214	sarcomere organization
GO:0051599	response to hydrostatic pressure
GO:0051707	response to other organism
GO:0060706	cell differentiation involved in embryonic placenta development
GO:0097191	extrinsic apoptotic signaling pathway
GO:0097284	hepatocyte apoptotic process

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005882	intermediate filament
GO:0005911	cell-cell junction
GO:0016010	dystrophin-associated glycoprotein complex
GO:0016363	nuclear matrix
GO:0030018	Z disc
GO:0042383	sarcolemma
GO:0043034	costamere
GO:0045095	keratin filament
GO:0070062	extracellular vesicular exosome
GO:0071944	cell periphery