Version 5.4
Homo sapiens Protein: EHD2
Summary
InnateDB Protein IDBP-595190.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EHD2
Protein Name EH-domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000439036
InnateDB Gene IDBG-59724 (EHD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000261 EPS15 homology (EH)
IPR001401 Dynamin, GTPase domain
IPR002048 EF-hand domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00350
PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00027
SM00053
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7ZAY3
UniProt Splice Variant
Entrez Gene 30846
UniGene Hs.726547
RefSeq
HUGO HGNC:3243
OMIM 605890
CCDS
HPRD 10434
IMGT
EMBL AC008745 AC010519 AK298067 AK300512 AK316448
GenPept BAG60358 BAG62224 BAH14819

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca