Homo sapiens Protein: EHF
Summary
InnateDB Protein IDBP-597651.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EHF
Protein Name ets homologous factor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000435835
InnateDB Gene IDBG-39419 (EHF)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 7 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007275 multicellular organismal development
GO:0008283 cell proliferation
GO:0030855 epithelial cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000418 Ets domain
IPR003118 Pointed domain
IPR013761 Sterile alpha motif/pointed domain
PFAM PF00178
PF02198
PRINTS PR00454
PIRSF
SMART SM00413
SM00251
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZC4
PhosphoSite PhosphoSite-Q9NZC4
TrEMBL E9PQX0
UniProt Splice Variant
Entrez Gene 26298
UniGene Hs.653859
RefSeq NP_001193545
HUGO HGNC:3246
OMIM 605439
CCDS CCDS55752
HPRD 16105
IMGT
EMBL AC087783 AF124438 AF124439 AF170583 AF203977 AF212848 AK310867 AL157952 AY882601 BC038995 CH471064
GenPept AAD30990 AAD30991 AAF06998 AAF61670 AAG35644 AAH38995 AAW80658 CAC12700 CAC12701 EAW68162 EAW68163 EAW68164 EAW68165 EAW68166