Version 5.4
Homo sapiens Protein: NUMB
Summary
InnateDB Protein IDBP-600608.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUMB
Protein Name numb homolog (Drosophila)
Synonyms c14_5527; C14orf41; S171;
Species Homo sapiens
Ensembl Protein ENSP00000452888
InnateDB Gene IDBG-11441 (NUMB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 45 [view]
Protein-Protein 45 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR006020 PTB/PI domain
IPR013625 Tensin phosphotyrosine-binding domain
IPR016698 Numb/numb-like
PFAM PF00640
PF14719
PF08416
PRINTS
PIRSF PIRSF017607
SMART SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5D0E5
UniProt Splice Variant
Entrez Gene 8650
UniGene Hs.714879
RefSeq
HUGO HGNC:8060
OMIM 603728
CCDS
HPRD 04767
IMGT
EMBL AC004846 AC005280 AL391733 BC033824
GenPept AAH33824

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca