InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGJ

Summary

InnateDB Protein

IDBP-600815.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGJ

Protein Name

immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

Synonyms

IGCJ; JCH;

Species

Homo sapiens

Ensembl Protein

ENSP00000440066

InnateDB Gene

IDBG-22626 (IGJ)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003697	single-stranded DNA binding
GO:0003823	antigen binding
GO:0019862	IgA binding
GO:0031210	phosphatidylcholine binding
GO:0034987	immunoglobulin receptor binding
GO:0042803	protein homodimerization activity
GO:0042834	peptidoglycan binding

Biological Process

GO:0001895	retina homeostasis
GO:0002250	adaptive immune response
GO:0003094	glomerular filtration
GO:0006955	immune response
GO:0019731	antibacterial humoral response
GO:0032461	positive regulation of protein oligomerization
GO:0045087	innate immune response
GO:0060267	positive regulation of respiratory burst

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome
GO:0071748	monomeric IgA immunoglobulin complex
GO:0071750	dimeric IgA immunoglobulin complex
GO:0071751	secretory IgA immunoglobulin complex
GO:0071752	secretory dimeric IgA immunoglobulin complex
GO:0071756	pentameric IgM immunoglobulin complex
GO:0072562	blood microparticle