Version 5.4
Homo sapiens Gene: IGJ
Summary
InnateDB Gene IDBG-22626.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGJ
Gene Name immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Synonyms IGCJ; JCH
Species Homo sapiens
Ensembl Gene ENSG00000132465
Encoded Proteins
IDBP-22628
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
IDBP-481936
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
IDBP-479703
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
IDBP-484901
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
IDBP-482850
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
IDBP-600815
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:70655541-70681817
Strand Reverse strand
Band q13.3
Transcripts
ENST00000254801 ENSP00000254801
ENST00000391614 ENSP00000426045
ENST00000510437 ENSP00000426687
ENST00000510614 ENSP00000427112
ENST00000470866 ENSP00000417560
ENST00000543780 ENSP00000440066
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003697 single-stranded DNA binding
GO:0003823 antigen binding
GO:0019862 IgA binding
GO:0031210 phosphatidylcholine binding
GO:0034987 immunoglobulin receptor binding
GO:0042803 protein homodimerization activity
GO:0042834 peptidoglycan binding
Biological Process
GO:0001895 retina homeostasis
GO:0002250 adaptive immune response
GO:0003094 glomerular filtration
GO:0006955 immune response
GO:0019731 antibacterial humoral response
GO:0032461 positive regulation of protein oligomerization
GO:0045087 innate immune response
GO:0060267 positive regulation of respiratory burst
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
GO:0071748 monomeric IgA immunoglobulin complex
GO:0071750 dimeric IgA immunoglobulin complex
GO:0071751 secretory IgA immunoglobulin complex
GO:0071752 secretory dimeric IgA immunoglobulin complex
GO:0071756 pentameric IgM immunoglobulin complex
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067149
View Gene Order
ENSBTAG00000018531
Not yet available
Cross-References
SwissProt
TrEMBL D6RD17
UniProt Splice Variant
Entrez Gene 3512
UniGene
RefSeq NM_144646 XM_006714211 XM_006714212
HUGO HGNC:5713
OMIM 147790
CCDS CCDS3545
HPRD 00991
IMGT
EMBL AC009570
GenPept
RNA Seq Atlas 3512

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca