InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FDFT1

Summary

InnateDB Protein

IDBP-601047.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDFT1

Protein Name

farnesyl-diphosphate farnesyltransferase 1

Synonyms

DGPT; ERG9; SQS; SS;

Species

Homo sapiens

Ensembl Protein

ENSP00000434714

InnateDB Gene

IDBG-7593 (FDFT1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.

Experimentally validated
Total	21 [view]
Protein-Protein	20 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004310	farnesyl-diphosphate farnesyltransferase activity
GO:0016740	transferase activity

Biological Process

GO:0008610	lipid biosynthetic process
GO:0009058	biosynthetic process

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002060 Squalene/phytoene synthase
IPR006449 Farnesyl-diphosphate farnesyltransferase
IPR008949 Terpenoid synthase

PFAM

PF00494

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PNM1

UniProt Splice Variant

Entrez Gene

2222

UniGene

Hs.736578

RefSeq

NP_001274685

HUGO

HGNC:3629

OMIM

184420

CCDS

HPRD

01694

IMGT

EMBL

AC069185 AK057726 AK293545 AK300059 AK315993 AK316351 AK316531 AK316534

GenPept

BAG51957 BAG61868 BAH11529 BAH14364 BAH14722 BAH14902 BAH14905